ABBV vs AZN

AbbVie and AstraZeneca PLC, both Healthcare

AbbVie is the larger company at $505B against $266B. Over the past year ABBV returned +28% against +3.4% for AZN. The RyuScore puts AZN ahead, 62 against 48 out of 100.

AbbVie and AstraZeneca PLC compared on valuation, return and the RyuScore
FigureABBVAZN
Last close$286$171
Market cap$505B$266B
Trailing P/Elower is cheaper for the same earnings, not automatically better80.7n/a
Dividend yield2.3%n/a
1-year return+28%+3.4%
5-year return+209%+55%
RyuScoresector-relative, 1–1048/10062/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

AbbVie

Revenue of $17B in Q2 2026, net income $3.6B. Its largest reported line is SKYRIZI, 36% of the disclosed total.

AstraZeneca PLC

Revenue of $31B in H2 2025, net income $4.9B.

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