AMGN vs AZN

Amgen and AstraZeneca PLC, both Healthcare

AstraZeneca PLC is the larger company at $266B against $237B. Over the past year AMGN returned +52% against +3.4% for AZN.

Amgen and AstraZeneca PLC compared on valuation, return and the RyuScore
FigureAMGNAZN
Last close$439$171
Market cap$237B$266B
Trailing P/Elower is cheaper for the same earnings, not automatically better27.3n/a
Dividend yield2.2%n/a
1-year return+52%+3.4%
5-year return+147%+55%
RyuScoresector-relative, 1–1062/10062/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Amgen

Revenue of $10B in Q2 2026, net income $2.4B. Its largest reported line is Other Products, 17% of the disclosed total.

AstraZeneca PLC

Revenue of $31B in H2 2025, net income $4.9B.

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