AMGN vs AZN

Amgen and AstraZeneca PLC, both Healthcare

AstraZeneca PLC is the larger company at $288B against $182B. On trailing earnings AMGN is the cheaper of the two at a P/E of 24.4 against 26.4, a gap that is only a bargain if the two are growing at similar rates. Over the past year AMGN returned +37% against +2.2% for AZN. Ryufin's sector-relative Smart Score puts AZN ahead, 9/10 against 7/10.

Amgen and AstraZeneca PLCcompared on valuation, return and Ryufin’s Smart Score
FigureAMGNAZN
Last close$393$160
Market cap$182B$288B
Trailing P/Elower is cheaper for the same earnings, not automatically better24.426.4
Dividend yield2.5%n/a
1-year return+37%+2.2%
5-year return+102%+57%
Ryufin Smart Scoresector-relative, 1–107/109/10

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Amgen

Revenue of $10B in Q2 2026, net income $2.4B. Its largest reported line is Other Products, 17% of the disclosed total.

AstraZeneca PLC

Revenue of $31B in H2 2025, net income $4.9B.

Open these two in the interactive comparison to add more names, change the period or see the correlation.