AMGN vs PFE

Amgen and Pfizer, both Healthcare

Amgen is the larger company at $182B against $144B. On trailing earnings AMGN is the cheaper of the two at a P/E of 24.4 against 36.6, a gap that is only a bargain if the two are growing at similar rates. Over the past year AMGN returned +37% against +16% for PFE. Ryufin's sector-relative Smart Score puts AMGN ahead, 7/10 against 5/10.

Amgen and Pfizercompared on valuation, return and Ryufin’s Smart Score
FigureAMGNPFE
Last close$393$27.80
Market cap$182B$144B
Trailing P/Elower is cheaper for the same earnings, not automatically better24.436.6
Dividend yield2.5%6.2%
1-year return+37%+16%
5-year return+102%-26%
Ryufin Smart Scoresector-relative, 1–107/105/10

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Amgen

Revenue of $10B in Q2 2026, net income $2.4B. Its largest reported line is Other Products, 17% of the disclosed total.

Pfizer

Revenue of $15B in Q2 2026, net income null. Its largest reported line is Eliquis, 16% of the disclosed total.

Open these two in the interactive comparison to add more names, change the period or see the correlation.