AMGN vs PFE

Amgen and Pfizer, both Healthcare

Amgen is the larger company at $237B against $171B. On trailing earnings AMGN is the cheaper of the two at a P/E of 27.3 against 39.5, a gap that is only a bargain if the two are growing at similar rates. Over the past year AMGN returned +52% against +30% for PFE. The RyuScore puts AMGN ahead, 62 against 59 out of 100.

Amgen and Pfizer compared on valuation, return and the RyuScore
FigureAMGNPFE
Last close$439$30.02
Market cap$237B$171B
Trailing P/Elower is cheaper for the same earnings, not automatically better27.339.5
Dividend yield2.2%5.8%
1-year return+52%+30%
5-year return+147%-8.6%
RyuScoresector-relative, 1–1062/10059/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Amgen

Revenue of $10B in Q2 2026, net income $2.4B. Its largest reported line is Other Products, 17% of the disclosed total.

Pfizer

Revenue of $15B in Q2 2026, net income null. Its largest reported line is Eliquis, 16% of the disclosed total.

Open these two in the interactive comparison to add more names, change the period or see the correlation.