XBIState Street SPDR S&P Biotech ETF

ETF · SPDR Series Trust

$152.49close Nov 6, 2026

The fund

Holdings as of Jun 30, 2026, filed with the SEC.

$10.7B

net assets, all share classes

0.35%

yearly cost, from the prospectus

161

positions on file

Growth of $100

Total return with dividends reinvested, month by month since July 2019.

$100$182
20192026
+91.7%

last 12 months

+24.1%

a year, over 3 years

+3.3%

a year, over 5 years

Largest holdings

The top 10 issuers of 161 positions, by share of the fund. Under each, about how much of the company the fund owns.

State Street Global AdvisorsCash and short-term
5.9%
Apogee Therapeutics Inc
1.5%

Most alike

The funds whose stock holdings overlap most with XBI's: stock by stock, the smaller of the two weights, added up.

The closest is IBB (iShares Biotechnology ETF): 40%of the two funds’ stock holdings are the same.

  1. IBBiShares Biotechnology ETF40% in common
  2. IWOiShares Russell 2000 Growth ETF13% in common
  3. VHTVanguard Health Care ETF13% in common
  4. VBKVanguard Small-Cap Growth ETF10% in common
  5. IWMiShares Russell 2000 ETF8.9% in common
  6. VTWOVanguard Russell 2000 ETF7.2% in common

XBI costs 0.35% a year. Overlap counts only the stocks we can match to a listing; bonds, cash and unmatched foreign shares are left out. Every group of near-identical funds and what each costs.

Sectors

The stocks we can place, by sector.

  • Healthcare94.1%
  • Financial Services0.5%

Countries

Where the holdings are, by share of the fund.

  • United States100.7%
  • Ireland1.2%
  • Bermuda1.2%
  • Netherlands1.0%
  • Switzerland1.0%
  • British Virgin Islands0.5%
  • Canada0.2%

What it holds

By kind of asset.

  • Stocks99.9%
  • Cash and short-term5.9%
  • Derivatives0.1%

From the fund’s Form N-PORT for June 2026 (filed Aug 28, 2026) and its prospectus, via the SEC’s public data sets. Shares of net assets can sum above 100% where a fund holds cash collateral or derivatives.