XBIState Street SPDR S&P Biotech ETF
ETF · SPDR Series Trust
The fund
Holdings as of Jun 30, 2026, filed with the SEC.
net assets, all share classes
yearly cost, from the prospectus
positions on file
Growth of $100
Total return with dividends reinvested, month by month since July 2019.
last 12 months
a year, over 3 years
a year, over 5 years
Largest holdings
The top 10 issuers of 161 positions, by share of the fund. Under each, about how much of the company the fund owns.
- State Street Global AdvisorsCash and short-term
- 5.9%
- Apogee Therapeutics Inc
- 1.5%
Where it owns the most
The companies of which XBI alone owns the largest share, from its holdings and each company's share count.
- NVAXNovavax, Inc.0.7% of the fund4.5% of the company
- SLSSELLAS Life Sciences Group, Inc.1.2% of the fund4.3% of the company
- NTLAIntellia Therapeutics, Inc.0.9% of the fund4.2% of the company
- ALTAltimmune, Inc.0.2% of the fund4.2% of the company
- SRPTSarepta Therapeutics, Inc.0.7% of the fund4.2% of the company
- OCGNOcugen, Inc.0.2% of the fund4.1% of the company
Most alike
The funds whose stock holdings overlap most with XBI's: stock by stock, the smaller of the two weights, added up.
The closest is IBB (iShares Biotechnology ETF): 40%of the two funds’ stock holdings are the same.
- IBBiShares Biotechnology ETF0.44% a year40% in common
- IWOiShares Russell 2000 Growth ETF0.24% a year13% in common
- VHTVanguard Health Care ETF0.09% a year13% in common
- VBKVanguard Small-Cap Growth ETF0.05% a year10% in common
- IWMiShares Russell 2000 ETF0.19% a year8.9% in common
- VTWOVanguard Russell 2000 ETF0.06% a year7.2% in common
XBI costs 0.35% a year. Overlap counts only the stocks we can match to a listing; bonds, cash and unmatched foreign shares are left out. Every group of near-identical funds and what each costs.
Sectors
The stocks we can place, by sector.
- Healthcare94.1%
- Financial Services0.5%
Countries
Where the holdings are, by share of the fund.
- United States100.7%
- Ireland1.2%
- Bermuda1.2%
- Netherlands1.0%
- Switzerland1.0%
- British Virgin Islands0.5%
- Canada0.2%
What it holds
By kind of asset.
- Stocks99.9%
- Cash and short-term5.9%
- Derivatives0.1%
From the fund’s Form N-PORT for June 2026 (filed Aug 28, 2026) and its prospectus, via the SEC’s public data sets. Shares of net assets can sum above 100% where a fund holds cash collateral or derivatives.