CSTLCastle Biosciences, Inc.
Is it safe?
Caution warranted: heavy debt (BB) and big price swings.
Insiders were net sellers (-$1.1M, 90 days to Oct 22, 2026), selling is often routine.
Net cash, but unprofitable, speculative. A rule of thumb on leverage, not a credit rating.
Large price swings, high volatility. Worst drawdown -88% · now 23% below its 52-week high.
Where this answer is blind. Altman sits structurally low for utilities and pipelines; Beneish runs high for fast growers, since sales growth alone lifts it; banks and REITs are excluded.
Can CSTL take a bad year?
Castle Biosciences, Inc. holds $257M more cash than debt, and is burning $122K a quarter, about 545.6 years of cover.
Net cash · as at Q2 2026 · cash and short-term investments less total debt
- Net debt / EBITDA
- net cash
Net debt / EBITDA · no net borrowings to measure against earnings
- Cash runway
- 5+ years
Cash runway · burning $122K a quarter at the current rate
- Annualised volatility
- 58%
Annualised volatility · S&P 500 16% · about 4 times the market's own swing
Details›
- Total debtQ2 2026
- $10M
- Cash and short-term investments
- $267M
- Net cash
- $257M
- EBITDA, trailing twelve months
- −$21M
- Operating profit, trailing twelve months
- −$32M
- Debt / equity
- 0.02×
- Annualised volatilitytwo years of daily moves
- 58%
- Worst drawdown on file
- −88%
- Below its 52-week high
- 23%
Balance sheet from SEC filings; drawdown and volatility from end-of-day closes; Altman Z from the filed statements.
The balance sheet
What it owes against what it owns, and how close that comes to trouble.
How far can it fall?
How much the price moves, how deep and how long its falls have run, and what each unit of risk has paid.
Diagnostics & Research
Ranks #10 of 21 by RyuScore