MDGLMadrigal Pharmaceuticals, Inc.

$433.63-1.9% 1Y

What is the market doing?

Mixed

No clear lean: nothing decisive, though heavily shorted (+10% of shares).

1 to watch, 2 neutral
TrendRangeboundderived · Oct 23, 2026

Rangebound, no clear trend. Oversold (RSI 25). Price is −14% vs its 200-day average.

Insider conviction−$6.6M (90 days to Oct 22, 2026)SEC EDGAR · Oct 22, 2026

Insiders were net sellers over the 90 days ending Oct 22, 2026; selling is often routine (taxes, diversification).

Short interest10% of sharesFINRA · Sep 30, 2026

Heavily shorted, settled Sep 30, 2026, more than a week of normal trading to cover, a crowded exit.

Against the whole market›

Percentile against every name Ryufin tracks. Higher is better; the tick marks the middle of the market. Context, not one of the checks above.

1-year returnmiddle of the market
vs 200-day avgbehind 77% of the market

Where this answer is blind. Insider selling is often routine (taxes, diversification); only cluster buying is a strong tell.

How MDGL is trading

Madrigal Pharmaceuticals, Inc. is −1.9% over the past year while the S&P 500 is +16%: 18 points behind the market.

−1.9%

1-year return · S&P 500 +16%

vs 200-day average
−14%

vs 200-day average · a clear downtrend

RSI (14)
25

RSI (14) · oversold, sold harder than it has been bought

Below its 52-week high
28%

Below its 52-week high

Oct 15, 2024$202.48 – $602.83 · dashed line: 200-day averageOct 23, 2026
Details›
Last close2026-10-23
$433.63
1 monthS&P 500 −0.94%
−16%
1 yearS&P 500 +16%
−1.9%
5 yearsS&P 500 +86%
+433%
vs 50-day average$506.75
−14%
52-week high
$602.83
52-week low
$412.35
Annualised volatility
52%
Insider selling, net, 6 monthsForms 3/4/5 to 2026-10-22
$2.1M
Calendar-year price return
YearReturn
2026 (year to date)−26%
2025+89%
2024+33%
2023−20%
2022+243%
2021−24%
2020+22%
2019−19%
2018+23%
2017+516%
Average return by calendar month, 2016–2026
MonthYearsPositiveAverage
Jan105 of 10+1.8%
Feb107 of 10+6.1%
Mar103 of 10−1.3%
Apr105 of 10+0.66%
May103 of 10+11%
Jun107 of 10+3.7%
Jul112 of 11−8.0%
Aug117 of 11+8.8%
Sep114 of 11+11%
Oct116 of 11+3.7%
Nov106 of 10+9.9%
Dec104 of 10+37%

End-of-day closes from IEX; the S&P 500 comparison uses SPY over the same window. Prices are a reference point, not a basis for trading decisions.

Where the price stands

Its trend against the 50-day and 200-day averages, and the levels it keeps coming back to.

What it has returned

With dividends, year by year, month by month, and by calendar month on average.

On our screens:Most shorted stocks