PRLDPrelude Therapeutics Incorporated

$3.63+130% 1Y

What is the market doing?

Mixed

No clear lean: rangebound and moderately shorted.

2 neutral, 1 without data
TrendRangeboundderived · Oct 23, 2026

Rangebound, no clear trend. Price is −9% vs its 200-day average.

Short interest5.7% of sharesFINRA · Sep 30, 2026

Moderately shorted, settled Sep 30, 2026, more than a week of normal trading to cover, a crowded exit.

Where this answer is blind. Insider selling is often routine (taxes, diversification); only cluster buying is a strong tell.

How PRLD is trading

Prelude Therapeutics Incorporated is +130% over the past year while the S&P 500 is +16%: 114 points ahead of the market.

+130%

1-year return · S&P 500 +16%

vs 200-day average
−8.6%

vs 200-day average · below trend, but not far

RSI (14)
45

RSI (14) · neutral

Below its 52-week high
45%

Below its 52-week high

Oct 21, 2024$0.61 – $6.62 · dashed line: 200-day averageOct 23, 2026
Details›
Last close2026-10-23
$3.63
1 monthS&P 500 −0.94%
−9.0%
1 yearS&P 500 +16%
+130%
5 yearsS&P 500 +86%
−78%
vs 50-day average$4.64
−22%
52-week high
$6.62
52-week low
$1.19
Annualised volatility
158%
Calendar-year price return
YearReturn
2026 (year to date)+25%
2025+127%
2024−70%
2023−29%
2022−51%
2021−83%
Average return by calendar month, 2020–2026
MonthYearsPositiveAverage
Jan61 of 6−16%
Feb62 of 6+3.8%
Mar64 of 6−2.7%
Apr63 of 6+5.5%
May61 of 6−11%
Jun62 of 6+2.2%
Jul62 of 6+7.4%
Aug64 of 6+18%
Sep61 of 6−18%
Oct73 of 7−16%
Nov63 of 6+19%
Dec64 of 6+23%

End-of-day closes from IEX; the S&P 500 comparison uses SPY over the same window. Prices are a reference point, not a basis for trading decisions.

Where the price stands

Its trend against the 50-day and 200-day averages, and the levels it keeps coming back to.

What it has returned

With dividends, year by year, month by month, and by calendar month on average.