PRMEPrime Medicine, Inc.
What is the market doing?
No clear lean: nothing decisive, though a crowded short (+18% of shares).
Choppy, but holding above its 200-day average. Price is +6% vs its 200-day average.
A crowded short, settled Sep 30, 2026, more than a week of normal trading to cover, a crowded exit.
Where this answer is blind. Insider selling is often routine (taxes, diversification); only cluster buying is a strong tell.
How PRME is trading
Prime Medicine, Inc. is −28% over the past year while the S&P 500 is +16%: 44 points behind the market.
1-year return · S&P 500 +16%
- vs 200-day average
- +5.7%
vs 200-day average · close to trend
- RSI (14)
- 56
RSI (14) · neutral
- Below its 52-week high
- 32%
Below its 52-week high
Details›
- Last close2026-10-23
- $3.68
- 1 monthS&P 500 −0.94%
- +5.7%
- 1 yearS&P 500 +16%
- −28%
- vs 50-day average$3.41
- +8.1%
- 52-week high
- $5.38
- 52-week low
- $2.70
- Annualised volatility
- 101%
| Year | Return |
|---|---|
| 2026 (year to date) | +6.1% |
| 2025 | +19% |
| 2024 | −67% |
| 2023 | −52% |
| Month | Years | Positive | Average |
|---|---|---|---|
| Jan | 4 | 1 of 4 | −7.0% |
| Feb | 4 | 2 of 4 | +10% |
| Mar | 4 | 0 of 4 | −22% |
| Apr | 4 | 2 of 4 | −7.2% |
| May | 4 | 2 of 4 | −0.08% |
| Jun | 4 | 3 of 4 | +25% |
| Jul | 4 | 3 of 4 | +11% |
| Aug | 4 | 1 of 4 | −6.5% |
| Sep | 4 | 1 of 4 | +4.6% |
| Oct | 4 | 2 of 4 | −5.5% |
| Nov | 4 | 1 of 4 | −8.7% |
| Dec | 4 | 2 of 4 | +2.4% |
End-of-day closes from IEX; the S&P 500 comparison uses SPY over the same window. Prices are a reference point, not a basis for trading decisions.
Where the price stands
Its trend against the 50-day and 200-day averages, and the levels it keeps coming back to.
What it has returned
With dividends, year by year, month by month, and by calendar month on average.