PSNLPersonalis, Inc.
Is the business good?
The checks split: margins widening, but 3 of 9 health tests passed.
Weak, deteriorating fundamentals. Nine pass/fail tests of year-over-year health from the filings.
Operating margin has widened over the past few years, the business is getting more profitable per dollar of sales.
Where this answer is blind. The F-score rewards improvement, so an already-elite company can score mid-pack.
How good a business is PSNL?
Personalis, Inc. spent more than it took in: an operating loss of $114M on $70M of revenue, 12 months to Q2 2026.
Operating loss · on $70M of revenue · 12 months to Q2 2026
- Share count, year on year
- +19%
Share count, year on year · shareholders own a smaller slice than a year ago
- R&D as % of revenue
- 81%
R&D as % of revenue
- Gross margin
- 13%
Gross margin
| Year | Operating margin |
|---|---|
| FY2020 | −54% |
| FY2021 | −76% |
| FY2022 | −178% |
| FY2023 | −150% |
| FY2024 | −81% |
| FY2025 | −126% |
Details›
- Gross margin12 months to Q2 2026
- 13%
- Operating margin12 months to Q2 2026
- −164%
- Net margin12 months to Q2 2026
- −154%
- Free cash flow margin
- −145%
- R&D as % of revenue
- 81%
- Revenue, trailing twelve months
- $70M
- Free cash flow, trailing twelve months
- −$101M
- Net income, trailing twelve months
- −$107M
Margins, capital and share counts from the statements as filed with the SEC; cash conversion is operating cash flow over operating profit after tax.
Customers and suppliers
Who buys from PSNL and who it buys from, as the companies report it.
- MRNAModerna22%
Share of revenue · FY2025 10-K
- U.S. government17%
Share of revenue · FY2025 10-K
None disclosed.
A company has to disclose every customer behind 10% or more of its revenue. Each share comes from the latest annual report of the company that states it and shows on both companies’ pages; PSNL’s own figures are from its FY2025 10-K. Smaller customers and suppliers go unreported.
Diagnostics & Research
Ranks #21 of 21 by RyuScore