SYRESpyre Therapeutics, Inc.

$90.35+306% 1Y

Is it safe?

Mixed

Forensics clean, with a caveat: a safe balance sheet, but big price swings.

1 good, 1 to watch, 1 neutral, 3 without data
SurvivalSafe zone

Financially healthy, low distress risk Altman Z-score, a bankruptcy-risk model from five balance-sheet ratios.

Insider conviction-$16.9M

Insiders were net sellers (-$16.9M, 90 days to Oct 22, 2026), selling is often routine.

Drawdown risk68% volderived · Oct 23, 2026

Large price swings, high volatility. Worst drawdown -99% · now 17% below its 52-week high.

Unless marked, from SEC EDGAR, as of Dec 31, 2025.

Against the whole market›

Percentile against every name Ryufin tracks. Higher is better; the tick marks the middle of the market. Context, not one of the checks above.

Volatilitybehind 85% of the market
Max drawdownbottom 1% of the market

Where this answer is blind. Altman sits structurally low for utilities and pipelines; Beneish runs high for fast growers, since sales growth alone lifts it; banks and REITs are excluded.

Can SYRE take a bad year?

The deepest fall in SYRE's price history on file is −99%; it is 17% below its high today.

74.61

Altman Z-score · distress below 1.8 · safe above 3 · safe zone, the balance sheet is not what threatens this one

Annualised volatility
68%

Annualised volatility · S&P 500 16% · about 4 times the market's own swing

Worst drawdown on file
−99%

Worst drawdown on file · −17% today

Details›
Cash and short-term investments
$1.15B
Operating profit, trailing twelve months
−$201M
Annualised volatilitytwo years of daily moves
68%
Worst drawdown on file
−99%
Below its 52-week high
17%

Balance sheet from SEC filings; drawdown and volatility from end-of-day closes; Altman Z from the filed statements.

The balance sheet

What it owes against what it owns, and how close that comes to trouble.

How far can it fall?

How much the price moves, how deep and how long its falls have run, and what each unit of risk has paid.

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