AZN vs MRK

AstraZeneca PLC and Merck & Co., both Healthcare

Merck & Co. is the larger company at $358B against $266B. Over the past year MRK returned +77% against +3.4% for AZN. The RyuScore puts MRK ahead, 76 against 62 out of 100.

AstraZeneca PLC and Merck & Co. compared on valuation, return and the RyuScore
FigureAZNMRK
Last close$171$145
Market cap$266B$358B
Trailing P/Elower is cheaper for the same earnings, not automatically bettern/a115.3
Dividend yieldn/a2.2%
1-year return+3.4%+77%
5-year return+55%+111%
RyuScoresector-relative, 1–1062/10076/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

AstraZeneca PLC

Revenue of $31B in H2 2025, net income $4.9B.

Merck & Co.

Revenue of $17B in Q2 2026, net income null. Its largest reported line is Keytruda, 49% of the disclosed total.

Open these two in the interactive comparison to add more names, change the period or see the correlation.