AZN vs NVS

AstraZeneca PLC and Novartis AG, both Healthcare

Novartis AG is the larger company at $288B against $266B. Over the past year NVS returned +19% against +3.4% for AZN. The RyuScore puts NVS ahead, 75 against 62 out of 100.

AstraZeneca PLC and Novartis AG compared on valuation, return and the RyuScore
FigureAZNNVS
Last close$171$151
Market cap$266B$288B
1-year return+3.4%+19%
5-year return+55%+121%
RyuScoresector-relative, 1–1062/10075/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

AstraZeneca PLC

Revenue of $31B in H2 2025, net income $4.9B.

Novartis AG

Revenue of $27B in H2 2025, net income $6.3B.

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